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KPT 9274 ( ATG-019) CAS:1643913-93-2

KPT 9274 ( ATG-019)

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-C-1127 25mg 425.00
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R-C-1127 50mg 675.00
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R-C-1127 100mg 1125.00
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Product description

KPT-9274,also known as PAK4-IN-1,is a potent,selective and dual PAK4/NAMPT inhibitor.KPT-9274 interferences with PAK4/NAMPT signaling pathways, which results in reduction of G2-M transit as well as induction of apoptosis and decrease in cell invasion and migration in several human RCC cell lines. Mechanistic studies demonstrate that inhibition of the PAK4 pathway by KPT-9274 attenuates nuclear β-catenin as well as the Wnt/β-catenin targets cyclin D1 and c-Myc.


Appearance N/A
Molecular Weight N/A
purity >95%
PDI by GPC <1.5
Solubility N/A
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 2 weeks
Stability 1 year
Document

msds---KPT 9274 ( ATG-019)
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